Can I Take the COVID Vaccination if I’m Feeling Unwell?

picture of a covid vaccine vial

Medically reviewed by Dr Welras Long (M.B.B.S, Singapore. MRCS, England)

The COVID-19 pandemic has highlighted the importance of vaccinations in controlling the spread of the virus and reducing severe illness. However, many people wonder whether they should proceed with their COVID vaccination if they are feeling unwell. 

Health authorities provide guidance on when to delay vaccination and when mild symptoms are not a cause for concern. Understanding these recommendations can help ensure the best possible immune response and minimise any risks associated with vaccination.

How the COVID Vaccine Works

The COVID vaccination stimulates the body’s immune system to recognise and fight the virus. It does this by introducing a harmless part of the virus that instructs the body to produce an immune response. 

This response includes the creation of antibodies and memory cells that help protect against future infections. To work effectively, the immune system needs to be in good condition, which is why some health experts advise against receiving the vaccine when acutely ill.

Mild Symptoms: Should You Delay the Vaccine?

If you have mild symptoms such as a runny nose, slight cough, or mild fatigue, vaccination is generally still safe. These minor symptoms do not significantly affect the body’s ability to mount an immune response. In fact, many people experience mild symptoms from common colds or allergies without their immune systems being significantly compromised.

However, if you are experiencing a fever or signs of an active infection, you may be advised to wait. A fever is a sign that the immune system is actively fighting off an infection, and introducing a vaccine at this time might not be ideal. Waiting until you have recovered allows the body to respond optimally to the vaccine.

Moderate to Severe Illness: When to Postpone Vaccination

If you have a moderate to severe illness, such as influenza, pneumonia, or another significant infection, postponing your COVID-19 vaccination is recommended. Severe illness can put stress on the body, making it more difficult for the immune system to respond effectively to the vaccine. Some signs that you should delay your vaccination include:

  • High fever (above 38.5°C)
  • Severe fatigue or body aches
  • Significant respiratory symptoms, such as difficulty breathing
  • Gastrointestinal symptoms like vomiting or diarrhea

Waiting until you have fully recovered before taking the vaccine helps ensure that your body can focus on building strong immunity against COVID-19.

Chronic Conditions and the COVID Vaccine

For individuals with chronic conditions such as asthma, diabetes, or heart disease, getting vaccinated is essential as they are at higher risk of severe COVID-19 complications. If you have a chronic condition but are experiencing mild symptoms, you may still proceed with vaccination. 

However, if your condition is flaring up or you are undergoing intensive medical treatment, it is advisable to consult a doctor before getting the vaccine.

How Many COVID-19 Vaccine Doses Do I Need?

For Individuals Who Haven’t Been Vaccinated

For unvaccinated individuals and those who started their COVID-19 vaccination in 2024/2025:

  • Children aged 6 months to 4 years should receive two doses, spaced eight weeks apart.
  • Individuals aged 5 years and above need just one dose.

For Those Already Vaccinated

For those that have previously received COVID-19 vaccination, it is recommended that they get an additional dose in 2024/2025. This should be given about one year—or at least five months—after the last dose.

Vaccination and Common Medications

Most medications do not interfere with the COVID-19 vaccine. 

However, if you are taking immunosuppressants or steroids, these drugs can affect your immune response. It is best to discuss vaccination timing with a doctor to ensure the best immune protection.

If you are taking antibiotics for an active bacterial infection, you may be advised to complete your course of medication before getting vaccinated. While antibiotics do not directly interact with vaccines, completing treatment helps ensure your body is in optimal condition for mounting a strong immune response.

Side Effects vs. Illness Symptoms

Some individuals worry about confusing vaccine side effects with illness symptoms. It is normal to experience mild side effects after vaccination, such as:

  • Soreness at the injection site
  • Mild fever or chills
  • Fatigue
  • Muscle aches

These side effects typically resolve within a day or two and indicate that the body is responding to the vaccine. However, if symptoms persist beyond a few days or worsen, it is important to seek medical attention to rule out other illnesses.

When to Seek Medical Advice

If you are unsure about whether to get vaccinated while feeling unwell, seeking medical advice is the best course of action. A healthcare provider can assess your symptoms and medical history to determine whether you should proceed with vaccination or delay it. Some key scenarios where medical consultation is recommended include:

  • Having a fever at the time of vaccination
  • A history of severe allergic reactions to previous vaccines
  • Experiencing a recent flare-up of a chronic condition
  • Currently taking immunosuppressive medications

Conclusion

Getting vaccinated against COVID-19 is one of the best ways to protect yourself and others from severe illness. While mild symptoms like a runny nose or mild fatigue usually do not prevent vaccination, moderate to severe illnesses may warrant a short delay. 

Ensuring that your body is in a stable condition before receiving the vaccine helps maximise immune response and effectiveness. If in doubt, consulting a healthcare professional is the best way to make an informed decision.

Book Your COVID-19 Vaccination with Keystone Clinic & Surgery!

If you need guidance on whether you should proceed with your COVID-19 vaccination, Keystone Clinic & Surgery offers expert consultations and vaccination services. Contact us today to schedule an appointment and ensure you receive the best medical care for your health and safety.

References

Prevention.com. Can You Get a COVID-19 Vaccine If You are Sick with Cold-Like Symptoms? Doctors Explain. https://www.prevention.com/health/a36186576/can-i-get-covid-19-vaccine-when-sick/

Emergencyhospitals.care. Can You Get the COVID Vaccine if You Have a Cold? https://www.emergencyhospitals.care/can-you-get-the-covid-vaccine-if-you-have-a-cold/

Yorkshirepost.co.uk. Can You Have Covid Vaccine if You Have a Cold? Latest Advice for Receiving Jab When Feeling Unwell Explained. https://www.yorkshirepost.co.uk/health/coronavirus/can-you-get-the-covid-vaccine-if-you-have-a-cold-3170657